Choosing the best herbicide for Creeping Charlie requires understanding its growth habits and selecting products that can effectively kill both the foliage and root system.

Creeping Charlie (Glechoma hederacea), also known as ground ivy, is one of the most persistent and challenging lawn weeds to control.

Creeping Charlie is an aggressive perennial that spreads rapidly through both seeds and creeping stems that root at the nodes.

This comprehensive guide examines the most effective herbicides for eliminating Creeping Charlie, including both chemical and organic options. We’ll cover application timing, techniques, and follow-up treatments to ensure complete eradication of this troublesome weed.

10 Best Herbicides for Creeping Charlie Control

1. Triclopyr Herbicide (Brush-B-Gon, Weed-B-Gon)–Best Selective Control for Creeping Charlie

Triclopyr is widely recognized as the most effective active ingredient for controlling Creeping Charlie. As a selective herbicide, it specifically targets broadleaf weeds while leaving most grasses unharmed. It works by mimicking natural plant hormones, triggering uncontrolled growth that eventually destroys the weed.

 

For optimal results, choose a product containing at least 8% triclopyr and apply during the fall season, when Creeping Charlie is moving nutrients into its roots. Mix 1.5 oz per gallon of water and always add a surfactant to ensure the herbicide sticks to the weed’s waxy leaves. A second treatment within 10–14 days often ensures complete eradication.

Research from university trials shows triclopyr achieves 85–95% control when used correctly. It is even more effective when combined in a three-way mix with other herbicides. This makes triclopyr one of the most reliable and proven solutions for long-term Creeping Charlie management.

Pros:

• Highly effective

• Selective action

• Grass safe

• Root targeted

• Research backed

• Combines well

• Long-lasting results

Cons:

• Needs surfactant

• Repeat required

• Limited availability

2. 2,4-D + Dicamba + MCPP – Best Three-Way Herbicide for Creeping Charlie

A three-way herbicide blend of 2,4-D, dicamba, and MCPP (mecoprop) is a proven solution for Creeping Charlie control. Each active ingredient attacks the weed through a different mode of action, making resistance much less likely to occur. When mixed with triclopyr, the effectiveness increases significantly.

 

The best time to apply is during spring or fall, when temperatures range between 60–85°F and Creeping Charlie is actively growing. Mix 2–3 oz per gallon of water and always include a surfactant for better absorption. A single treatment typically provides 70–80% control, though follow-up applications are often required.

This three-way combination is especially valuable for lawns with multiple broadleaf weeds. In addition to Creeping Charlie, it also suppresses dandelions, clover, and plantain, making it versatile for turf management. With consistent use, it provides broad coverage and reliable results for homeowners and professionals alike.

Pros:

• Multi-action control

• Reduces resistance

• Versatile mix

• Broadleaf coverage

• Works with triclopyr

• Reliable results

• Temperature flexible

Cons:

• Needs surfactant

• Follow-up required

• Moderate control

3. Borax (Sodium Tetraborate)

Borax provides an organic alternative for suppressing Creeping Charlie, but it must be applied with precision. The boron content in borax is toxic to Creeping Charlie, effectively damaging its growth. However, in high concentrations, it can also harm grass and other desirable plants, making careful use essential.

 

To apply, mix 10 oz of 20 Mule Team Borax into 2.5 gallons of water, treating around 1,000 sq ft of lawn. The best time for application is in the fall season, when Creeping Charlie is actively growing but temperatures remain below 85°F. It is crucial to avoid overlapping treatments and to limit usage to once per year.

Research indicates borax provides 60–70% control of Creeping Charlie when applied properly. This method works best for small, targeted areas rather than large-scale lawn treatments. While not a permanent solution, borax offers a natural approach for those seeking organic weed management.

Pros:

• Organic option

• Affordable method

• Easy to mix

• Effective fall use

• Safe alternative

• Targets weeds

• Visible results

Cons:

• Grass risk

• Limited coverage

• Annual use only

4. Clopyralid (Stinger, Lontrel)-– Selective Herbicide for Creeping Charlie

Clopyralid is a selective herbicide that works exceptionally well on creeping perennials in the mint family, including Creeping Charlie. It is absorbed through both the leaves and roots, delivering systemic control that eliminates the entire plant. This makes it a strong option for long-term suppression.

 

The proper application rate is 0.25–0.5 oz per gallon of water in either spring or fall, when Creeping Charlie is most active. Adding a non-ionic surfactant improves coverage and increases effectiveness. With correct use, clopyralid provides 80–90% control, though follow-up treatments may be necessary for full eradication.

One important consideration is clopyralid’s long soil residual activity, which means it can persist in treated areas. Sensitive plants like vegetables and ornamentals may be affected if compost or mulch from treated sites is reused. Because of this, users must apply carefully and avoid contamination of desirable plant beds.

Pros:

• Selective control

• Systemic action

• High effectiveness

• Root absorption

• Leaf absorption

• Long residual

• Consistent results

Cons:

• Sensitive plants risk

• Compost issues

• Follow-up needed

5. Glyphosate (Roundup, Rodeo)-Non-Selective Herbicide for Creeping Charlie

Glyphosate is a widely used non-selective herbicide that kills Creeping Charlie along with any surrounding grass or plants it touches. Because of this, it is best suited for spot treatments or in areas where total vegetation removal is acceptable. Its strength lies in its ability to penetrate deeply and kill the roots.

 

The recommended mixture is a 2% solution (2.6 oz per gallon), applied carefully to Creeping Charlie foliage. For maximum effectiveness, apply in the fall season, when the plant is moving nutrients down to its roots. A single treatment often provides 90–95% control, though multiple applications may be necessary for complete eradication.

When dealing with lawn areas, glyphosate should only be considered for full renovation projects. After application, reseeding or laying sod can be done once the chemical breaks down in 7–10 days. This approach ensures a clean slate while preventing the weed from quickly returning.

Pros:

• Highly effective

• Kills roots

• Fast results

• Widely available

• Long-lasting control

• Easy mixing

• Strong systemic

Cons:

• Non-selective

• Kills grass

• Repeat needed

6. Iron HEDTA (Fiesta, Iron-X)– Organic Herbicide for Creeping Charlie

Iron HEDTA is an organic-based herbicide that targets broadleaf weeds by inducing oxidative stress in plant tissues. While it is not as powerful as synthetic herbicides, it offers a safer option for use in areas where children and pets are frequently present. This makes it ideal for homeowners who prefer eco-friendly lawn care solutions.

 

For proper use, apply 6–10 oz per gallon of water and ensure full coverage of Creeping Charlie foliage. Applications should be repeated every 10–14 days until desired results are achieved. Multiple treatments generally provide 50–60% control, making persistence important for success.

This herbicide is most effective on young and actively growing Creeping Charlie plants. It is less effective against mature or heavily established patches, meaning timing plays a key role in achieving results. With consistent applications, Iron HEDTA can provide a balance between safety and control.

Pros:

• Organic option

• Child safe

• Pet friendly

• Eco-friendly

• Easy to apply

• Visible results

• Lawn safe

Cons:

• Limited control

• Repeated use

• Less effective mature

7. Fluroxypyr (Spotless, Vista)-Selective Herbicide for Creeping Charlie

Fluroxypyr is a selective herbicide designed to target Creeping Charlie and other stubborn broadleaf weeds. It is considered safe for use on most turfgrasses, making it a popular choice for lawns. This product is especially effective when combined with triclopyr or 2,4-D for enhanced weed control.

 

For best results, apply 0.5–1 oz per gallon of water during spring or fall when Creeping Charlie is actively growing. Adding a surfactant improves absorption and ensures better contact with the weed’s foliage. With consistent use, fluroxypyr achieves 75–85% control, though follow-up treatments are often required.

Another strength of this herbicide is its reliability in cool temperatures, particularly in early spring when other herbicides may lose effectiveness. This makes it a versatile option for lawn managers and homeowners dealing with tough infestations. When used correctly, it balances safety for grass with strong suppression of Creeping Charlie.

Pros:

• Selective action

• Safe on grass

• Broadleaf control

• Mix compatible

• Works in cool

• Reliable results

• Turf friendly

Cons:

• Needs surfactant

• Follow-up required

• Moderate control

8. Aminocyclopyrachlor (Method, Imprelis)-Professional Herbicide for Creeping Charlie

Aminocyclopyrachlor is a professional-grade herbicide that delivers systemic control against Creeping Charlie. Unlike contact herbicides, it is absorbed through both the leaves and roots, ensuring that the entire plant is killed. This makes it one of the most powerful control options available.

 

The recommended application rate is 0.5–1 oz per gallon of water, typically in spring or fall when weeds are most active. A single application can achieve 90–95% control, offering long-lasting results compared to organic or weaker chemical methods. However, this herbicide is restricted to licensed applicators in many regions.

A key consideration with aminocyclopyrachlor is its long soil residual activity, which means it can persist in the soil for an extended time. While this improves control, it may also harm sensitive plants if not applied with caution. Careful handling and professional oversight are crucial to prevent unintended damage.

Pros:

• Systemic action

• Long-lasting control

• High effectiveness

• Single application

• Absorbed by roots

• Absorbed by leaves

• Professional standard

Cons:

• Licensed use

• Soil persistence

• Sensitive plants risk

9. Horticultural Vinegar (20-30% Acetic Acid)- Natural Weed Control for Creeping Charlie

Horticultural vinegar is stronger than household vinegar, containing 20–30% acetic acid. It works by desiccating plant tissues, which causes visible damage to the leaves of Creeping Charlie. However, this method does not penetrate the roots, so repeated applications are often required for effective control.

 

To use horticultural vinegar effectively, apply it undiluted on a sunny day directly to the Creeping Charlie foliage. This treatment should be repeated every 7–10 days until the weed population is reduced. Research shows it can provide around 40–50% control when applied consistently.

This organic solution is best suited for smaller patches of Creeping Charlie where precision application is possible. Care must be taken to avoid drift onto nearby grass or desirable plants, as vinegar can damage them. While not a complete eradication method, it serves as a safer alternative to synthetic herbicides.

Pros:

• Organic option

• Immediate action

• Easy application

• Eco-friendly

• Non-toxic soil

• Affordable method

• Visible results

Cons:

• Root survival

• Repeat needed

• Risk to plants

10. Quinclorac (Drive, Quinclorac 75DF)

Quinclorac is primarily a grass herbicide but can help control Creeping Charlie when mixed with other broadleaf herbicides like 2,4-D or triclopyr. It provides an additional mode of action that enhances overall control.

 

Mix 0.5 oz quinclorac with 1 oz triclopyr per gallon of water and apply in fall. This combination can provide 80-90% control of Creeping Charlie with proper application.

Quinclorac is particularly useful in lawns where both grassy weeds and Creeping Charlie are problems.

Buyer Tips Guide for the Best Herbicide for Creeping Charlie

Selecting the right herbicide for Creeping Charlie requires careful consideration of several factors. Here are seven essential buyer tips to help you choose the most effective product:

1. Choose the Right Active Ingredient
Triclopyr is the most effective single ingredient against Creeping Charlie. For best results, look for products containing triclopyr alone or in combination with other herbicides like 2,4-D and dicamba.

2. Consider Application Timing
Fall (September-October) is the best time to treat Creeping Charlie, as plants are actively storing nutrients in their roots. Spring applications can also work but may require follow-up treatments.

3. Use Proper Mixing Ratios
Always follow label instructions for mixing rates. Adding a surfactant (1 tsp per gallon) helps herbicides adhere to Creeping Charlie’s waxy leaves and improves absorption.

4. Plan for Multiple Applications
Creeping Charlie often requires 2-3 applications spaced 10-14 days apart for complete control. The first application weakens the plant, while follow-up treatments kill regrowth.

5. Match Herbicide to Your Lawn Type
Some herbicides can damage certain grass types. Check product labels to ensure compatibility with your lawn grass before application.

6. Consider Environmental Factors
Avoid applying herbicides when rain is expected within 24 hours or when temperatures exceed 85°F. Ideal application conditions are calm days with temperatures between 60-80°F.

7. Combine Chemical and Cultural Controls
For long-term control, improve lawn health through proper mowing, fertilization, and aeration to prevent Creeping Charlie from re-establishing after herbicide treatment.

Conclusion

In conclusion, triclopyr-based herbicides provide the most effective control of Creeping Charlie, especially when applied in fall as part of a multi-treatment program.

For organic options, borax and iron HEDTA  Creeping Charlie herbicides  can provide partial control but require more frequent applications.

Always follow label instructions carefully when applying any herbicide.

Remember that complete eradication of Creeping Charlie often requires both herbicide treatment and cultural practices to maintain a thick, healthy lawn that resists weed invasion.